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Biologically Active 2-oxazolidinone Derivatives beyond Antibacterial Activities.

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2-oxazolidinone is well known as a pharmacophore for antibacterial agents represented by two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing reports on the various biological… Click to show full abstract

2-oxazolidinone is well known as a pharmacophore for antibacterial agents represented by two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing reports on the various biological activities of 2-oxazolidinones beyond antibacterial activities. Therefore, in this review, we provide an overview of the progress of this untraditional area of 2-oxazolidinones in the past 10 years (2011-2021).

Keywords: beyond antibacterial; active oxazolidinone; oxazolidinone derivatives; antibacterial activities; derivatives beyond; biologically active

Journal Title: Current medicinal chemistry
Year Published: 2022

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