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Chloroquinoline-3-carbonitriles: Synthesis and Reactions

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We herein describe the first review which aims to focus soberly the various synthetic methods and chemical reactions of chloroquinoline-3-carbonitrile derivatives. The reactions are subdivided into groups that cover reactions… Click to show full abstract

We herein describe the first review which aims to focus soberly the various synthetic methods and chemical reactions of chloroquinoline-3-carbonitrile derivatives. The reactions are subdivided into groups that cover reactions of chloro substituent at 2 or 4 and 2,4 positions, as well as cyano substituent at 3 position and reactions which involve both groups. Most types of reactions have been successfully applied and used in the production of biologically active compounds.

Keywords: synthesis reactions; chemistry; reactions chloroquinoline; carbonitriles synthesis; chloroquinoline carbonitriles

Journal Title: Current Organic Chemistry
Year Published: 2019

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