LAUSR

1,4-benzodiazepines play a valuable role in organic and medicinal chemistry. In this review article, we have mainly discussed the synthesis of various 1,4-benzodiazepines in the presence of a palladium catalyst. Different reactions, such as intramolecular N-arylation, reductive elimination, oxidative addition, intramolecular alkylation, C-H activation, aryl-aryl bond formation, etc., are included. For these types of syntheses, an easy and efficient catalytic domino process has been reported, including the intermolecular or intramolecular reactions. In this review article, we have also discussed catalyst regeneration and some ligand-free Pd-catalyzed reactions.