LAUSR

Nanoemulsions have attracted tremendous consideration of scientific community across the globe in recent years as the most promising strategy of drug delivery, targeting potential, bioavailability enhancement etc. These are efficient heterogeneous dispersions comprising of oily and aqueous phases, and can be stabilized by surfactants and co-surfactants. Such fascinating and sophisticated systems can improve the bioavailability of various therapeutic entities along with precise targeting of specific organs. Additionally, nano-sized emulsions of various actives offer numerous salient benefits such as effective release of drug, extended efficacy, controlled drug utilization, lesser adverse effects and fortification of drug from degradation whether enzymatic or oxidative. Nanotech based emulsions also facilitate remarkable and wonderful pharmaceutical and cosmeceutical applications through myriad technological approaches. By perfectly controlling the composition, arrangement of nanoemulsion ingredients and technique of preparation, nanoemulsions with desired attributes and high performance can be developed. The rationale of this review is to represent salient advantages, formulation techniques, characterization aspects and promising applications of various multitalented and impressive nanoemulsions. Current marketed formulations, recent patents, significant clinical practices etc. in the vistas of nanoemulsion technology are also highlighted in the present manuscript. This review also provides deep insights on the precise attributes, utilization facts and stability aspects of various nanoemulsions. Elucidation of scientific advancements in conjunction with encouraging findings concerning the future perspectives and challenges of nanoemulsions has also been discussed. Relevant literature for this manuscript was collected from comprehensive and systematic search of databases for example PubMed, Science Direct, Google Scholar and others using specific keyword combination, including "pharmaceutical nanoemulsions", "nanoemulsions for drug delivery", "applications of nanoemulsions" and several others.