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COVID-19-Associated Coagulopathy: Role of Vitamins D and K.

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Recent reports show coagulopathy as a potential complication and poorer outcome of coronavirus disease 2019 (COVID-19), especially in those with comorbid conditions such as diabetes and hypertension as thrombosis could… Click to show full abstract

Recent reports show coagulopathy as a potential complication and poorer outcome of coronavirus disease 2019 (COVID-19), especially in those with comorbid conditions such as diabetes and hypertension as thrombosis could result in stroke and heart attacks. Indeed, cardiovascular complications in COVID-19 accounts for 40% of mortality. Although there is no standard treatment protocol or guidelines for COVID-19, it is a common practice to use anti-inflammatory corticosteroids and anti-coagulants, especially for severe COVID-19 patients. It has also been confirmed that deficiencies in vitamin D and/or vitamin K can exacerbate premorbid cardiovascular and diabetes conditions associated with COVID-19, at least partially due to higher incidence of coagulopathy. Here, we discuss the roles of vitamins D and K and their roles in COVID-19-related coagulopathy. Moreover, suggestion for proper supplementations of these vitamins in countering COVID-19 is provided.

Keywords: associated coagulopathy; coagulopathy role; role vitamins; covid; covid associated

Journal Title: Current pharmaceutical biotechnology
Year Published: 2022

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