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A Comparison of biomarkers in assessment of glycemic control in diabetes: Reviewing the Evidence.

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BACKGROUND Diabetes mellitus (DM) is a chronic life-long progressive multisystem heterogeneous metabolic disorder with complex pathogenesis. INTRODUCTION Hyperglycemia is not only one of the classical signs of DM, but it… Click to show full abstract

BACKGROUND Diabetes mellitus (DM) is a chronic life-long progressive multisystem heterogeneous metabolic disorder with complex pathogenesis. INTRODUCTION Hyperglycemia is not only one of the classical signs of DM, but it also serves as the pivotal prerequisite for the diagnosis of the disease. However, with advancement in the field of analytical biochemistry, a number of alternative and specific biomarkers have been discovered which can be used for the better diagnosis of the DM. In this review, we have discussed various aspects of DM and different biomarkers used in assessing glycemia. METHODOLOGY A thorough literature survey was conducted to identify various studies that reported the use of conventional and non-conventional markers for the assessment of glycemia in DM patients. CONCLUSION The accurate detection and hence diagnosis of DM has become easy and more specific with the use of various biomarkers.

Keywords: biomarkers assessment; control diabetes; diabetes reviewing; glycemic control; comparison biomarkers; assessment glycemic

Journal Title: Current diabetes reviews
Year Published: 2019

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