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Recent Opportunities and Challenges in Selective C-H Functionalization of Methyl Azaarenes: a Highlight from 2010 to 2020 Literatures.

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Azaarenes are unique scaffolds frequently found in pharmaceuticals. Herein, we have summarized the recent synthetic available methods in C-H functionalization of methylazaarenes from 2010 to 2020. Multiple approaches involving halogenation… Click to show full abstract

Azaarenes are unique scaffolds frequently found in pharmaceuticals. Herein, we have summarized the recent synthetic available methods in C-H functionalization of methylazaarenes from 2010 to 2020. Multiple approaches involving halogenation and alkylation via different methods, such as alkenylation, oxidative functionalization, and cyclization of the methylazaarenes will be discussed in this review.

Keywords: 2010 2020; challenges selective; selective functionalization; opportunities challenges; recent opportunities; functionalization

Journal Title: Current organic synthesis
Year Published: 2021

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