LAUSR

Cardiovascular Diseases (CVDs) are a leading cause of death worldwide and impose an enormous clinical and economic burden on humanity [1]. In 2015, a Global Burden of Cardiovascular Disease study showed that CVDs accounted for one-third of all deaths per year, and the estimated patient population of 422.7 million [2]. The prevalence is becoming higher in 2018 owing to the progressive aging of the global population as well as insufficient exploration of CVDs pathogenesis. Since formally recognized as a major concern for global health by the United Nations in 2011 [3], CVDs have continued to be a research hotspot in which all countries attempt to dramatically reduce their impact. Therefore, it is very necessary to carry out new research to prevent and treat CVDs globally.