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Current Challenges and Implications of Proteogenomic Approaches in Prostate Cancer.

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In the recent past, next-generation sequencing (NGS) approaches have heralded the omics era. With NGS data burgeoning, there arose a need to better disseminate the omic data deluge. Proteogenomics has… Click to show full abstract

In the recent past, next-generation sequencing (NGS) approaches have heralded the omics era. With NGS data burgeoning, there arose a need to better disseminate the omic data deluge. Proteogenomics has been vividly used for characterising the functions of candidate genes and are applied in ascertaining various diseased phenotypes including cancers. However, not much is known about the role and application of proteogenomics especially in case of Prostate Cancer (PCa). In this review, we outline the need for proteogenomic approaches, their applications and its role in PCa.

Keywords: proteogenomic approaches; implications proteogenomic; current challenges; prostate cancer; challenges implications

Journal Title: Current topics in medicinal chemistry
Year Published: 2020

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