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Therapeutic Potential of microRNA Against Th2-associated Immune Disorders.

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MicroRNAs (miRNAs) are short ~18-22 nucleotide, single-stranded, non-coding RNA molecules playing a crucial role in regulating diverse biological processes, and are frequently dysregulated during disease pathogenesis. Thus, targeting miRNA could… Click to show full abstract

MicroRNAs (miRNAs) are short ~18-22 nucleotide, single-stranded, non-coding RNA molecules playing a crucial role in regulating diverse biological processes, and are frequently dysregulated during disease pathogenesis. Thus, targeting miRNA could be a potential candidate for therapeutic invention. This systemic review aims to summarize our current understanding regarding the role of miRNAs associated with Th2-mediated immune disorders and strategies for therapeutic drug development and current clinical trials.

Keywords: th2 associated; associated immune; microrna th2; therapeutic potential; immune disorders; potential microrna

Journal Title: Current topics in medicinal chemistry
Year Published: 2021

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