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There is a need to explore natural compounds against COVID-19 due to their multi-targeted actions against various targets of nCoV. They act on multiple sites rather than single targets against… Click to show full abstract
There is a need to explore natural compounds against COVID-19 due to their multi-targeted actions against various targets of nCoV. They act on multiple sites rather than single targets against several diseases. Thus, there is a possibility that the natural resources can be repurposed to combat the COVID-19. However, the biochemical mechanisms of these inhibitors were not known. To reveal the mode of anti-nCoV action, structure-based docking plays a major role. The present study is an attempt to explore various potential targets of SARS-CoV-2 and the structure-based screening of various potential natural inhibitors to combat the novel corona virus.
Journal Title: Current topics in medicinal chemistry
Year Published: 2022
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