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Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents.

Fused triazole had explored their apartment as one of the important class of heterocycles, extensively used by chemists due to their diverse pharmacological activities in both synthetic organic chemistry and… Click to show full abstract

Fused triazole had explored their apartment as one of the important class of heterocycles, extensively used by chemists due to their diverse pharmacological activities in both synthetic organic chemistry and systemic biological field. Various methodologies for targets containing fused thiazole scaffold were reported in literature with their potent pharmacological activities. Thiazole and its hybrid compounds had attracted attention to design novel anticancer agents. Currently, various fused thiazole containing compounds are available in market to cure cancer. This review focus on different methodologies and anticancer activity of various fused and tethered thiazole containing compounds. The anticancer property of different novel entities was extensively studied and can be surely proved a promising lead for the drug development.

Keywords: fused thiazoles; synthetic medicinal; anticancer agents; perspective fused; chemistry; medicinal perspective

Journal Title: Anti-cancer agents in medicinal chemistry
Year Published: 2020

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