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Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes

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Brain butyrylcholinesterase (BChE) is an attractive target for drugs designed for the treatment of Alzheimer’s disease (AD) in its advanced stages. It also potentially represents a biomarker for pr... Click to show full abstract

Brain butyrylcholinesterase (BChE) is an attractive target for drugs designed for the treatment of Alzheimer’s disease (AD) in its advanced stages. It also potentially represents a biomarker for pr...

Keywords: development potent; selective inhibitors; potent reversible; inhibitors butyrylcholinesterase; reversible selective; butyrylcholinesterase fluorescent

Journal Title: Journal of Enzyme Inhibition and Medicinal Chemistry
Year Published: 2020

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