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Axonal transport proteins as biomarkers of neurodegeneration?

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Neurodegeneration is a cardinal feature of numerous neurological diseases, yet the mechanisms underlying neurodegeneration are disparate and are not currently fully understood. In addition, the diagnosis of neurodegenerative conditions is… Click to show full abstract

Neurodegeneration is a cardinal feature of numerous neurological diseases, yet the mechanisms underlying neurodegeneration are disparate and are not currently fully understood. In addition, the diagnosis of neurodegenerative conditions is often challenging and treatments are limited. Nevertheless, new therapeutic strategies and trials are being developed and, as a result, better biomarkers of disease severity, progression and prognosis are required in order to monitor the efficacy of new treatments.

Keywords: biomarkers neurodegeneration; transport proteins; axonal transport; proteins biomarkers

Journal Title: Biomarkers in medicine
Year Published: 2017

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