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Inflammation is a defensive response that helps repair and restore damaged tissue by activating immune and nonimmune cells against pathogens. However, inflammation may cause chronic disease if it persists for a… Click to show full abstract
Inflammation is a defensive response that helps repair and restore damaged tissue by activating immune and nonimmune cells against pathogens. However, inflammation may cause chronic disease if it persists for a long time. Neutrophils recruit immediately to the lesion site and regulate the inflammatory process when inflammation occurs. Therefore, neutrophil-mediated therapy has been considered as a promising strategy for inflammatory diseases and has been extensively studied. In this review, we summarize the recent research progress of neutrophil-based personalized treatment strategies for inflammation. We also review the research progress of various neutrophil-mediated drug-delivery systems in combination with the inflammatory microenvironment.
Journal Title: Nanomedicine
Year Published: 2023
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