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Macrosomia is one of the most frequent complications in women with hyperglycemia in pregnancy, and advanced glycation end products (AGEs) may play a role in fetus growth. We were very… Click to show full abstract
Macrosomia is one of the most frequent complications in women with hyperglycemia in pregnancy, and advanced glycation end products (AGEs) may play a role in fetus growth. We were very interested by the article by Foussard et al. (1) reporting a positive association in women with pregestational diabetes or hyperglycemia in pregnancy between maternal skin autofluorescence (sAF), an estimate of AGE accumulation, and large-for-gestational-age (LGA) newborns or infants with birth weight >4,000 g. This association remained significant after adjustment for HbA1c, suggesting that, besides hyperglycemia, other factors might be involved in the relation between sAF and macrosomia. We had the opportunity to explore the relationship between sAF and …
Journal Title: Diabetes
Year Published: 2020
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