Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare form of primary localized cutaneous amyloidosis characterized clinically by solitary or multiple nodules. Although the prognosis is usually good, an extensive… Click to show full abstract
Primary localized cutaneous nodular amyloidosis (PLCNA) is a rare form of primary localized cutaneous amyloidosis characterized clinically by solitary or multiple nodules. Although the prognosis is usually good, an extensive work-up must be performed in all patients with PLCNA, since it is both clinically and histopathologically indistinguishable from systemic amyloidosis in up to 40% of cases. Recently, high-frequency ultrasound (HFUS) has emerged as a non-invasive imaging method in dermatology. It has been shown to be of significant value for the study of certain skin tumours or inflammatory conditions. To our knowledge there are no published reports of ultrasound findings in PLCNA. We report here a case of PLCNA with dystrophic calcification with ultrasound findings. Dystrophic calcification is rarely found in PLCNA, but has been reported in cases of localized amyloidosis of other organs. Thus, we suggest that PLCNA should be included in the differential diagnosis of subcutaneous nodules with dystrophic calcification. CASE REPORT
               
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