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1Department of Radiology, Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands 2Department of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands 3Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands 4Department of Radiology and Nuclear Imaging, Amsterdam UMC, Amsterdam, The Netherlands 5Department of Orthopedics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands *Corresponding author, Phone: +31-50-3612205, E-mail: [email protected]