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Evaluation of Phytochemicals of Cassia tora Linn. and it’s Cytotoxicity Assay using Brine Shrimp

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Cassia tora Linn. is a well known medicinal herb found as a rainy season weed throughout India. Various studies have been conducted in order to find out the applications of… Click to show full abstract

Cassia tora Linn. is a well known medicinal herb found as a rainy season weed throughout India. Various studies have been conducted in order to find out the applications of Cassia tora since many years and found various phytochemical present in the plant, contribute to the use of traditional medicine. Cytotoxicity of the plant is found due to some phytochemical present in the plant and thus this plant has found numerous applications in the medical field. Research Objective: The main aim of the research was to assess the effect of cytotoxicity of the plant extracts against Artemia salina. Brine shrimp lethality assay was used in this study to carry out the cytotoxicity assay. Thus, this research paper emphasizes on the screening of phytochemicals present in the various parts of the plant along with the cytotoxicity assay against Artemia salina. Results and Conclusion: The present study showed that the presence of phytochemicals vary with the plant parts and the effect of cytotoxicity on Brine shrimp was also observed with the LD50 value less than 100 μg/ mL which can be beneficial in the treatment of various cancers and tumors.

Keywords: cytotoxicity assay; plant; cassia tora; brine shrimp; tora linn; cytotoxicity

Journal Title: Phytopathology
Year Published: 2017

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