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Lipofuscin Deposition in the Kidney: Damaging or Deceiving?

Lipofuscin is an intracellular deposit comprising proteins and lipids that accumulate with aging. Lipofuscin deposition in native human kidneys is rarely reported. A 51-year-old hypertensive female suffering from chronic kidney… Click to show full abstract

Lipofuscin is an intracellular deposit comprising proteins and lipids that accumulate with aging. Lipofuscin deposition in native human kidneys is rarely reported. A 51-year-old hypertensive female suffering from chronic kidney disease presented with unexplained GFR deterioration. Kidney biopsy revealed extensive golden-brown lipofuscin pigment deposition in renal tubules.

Keywords: damaging deceiving; deposition kidney; deposition; lipofuscin deposition; kidney damaging; kidney

Journal Title: Indian Journal of Nephrology
Year Published: 2025

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