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Acute and chronic effects of a light-activated FGF receptor in keratinocytes in vitro and in mice

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Optogenetic activation of FGFR2 allowed temporally precise induction of signaling and behavioural changes, but counter-regulation at multiple levels prevented a sustained response in keratinocytes. Click to show full abstract

Optogenetic activation of FGFR2 allowed temporally precise induction of signaling and behavioural changes, but counter-regulation at multiple levels prevented a sustained response in keratinocytes.

Keywords: fgf receptor; light activated; activated fgf; chronic effects; acute chronic; effects light

Journal Title: Life Science Alliance
Year Published: 2021

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