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Expression of TMPRSS2 is up-regulated by bacterial flagellin, LPS, and Pam3Cys in human airway cells

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The expression of the virus-activating protease TMPRSS2 in airway cells is enhanced by bacterial components. This may contribute to virus activation and replication in co-infections of IAV and bacteria. Click to show full abstract

The expression of the virus-activating protease TMPRSS2 in airway cells is enhanced by bacterial components. This may contribute to virus activation and replication in co-infections of IAV and bacteria.

Keywords: regulated bacterial; tmprss2 regulated; expression; expression tmprss2; bacterial flagellin; airway cells

Journal Title: Life Science Alliance
Year Published: 2023

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