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Prostaglandin F2α regulates mitochondrial dynamics and mitophagy in the bovine corpus luteum

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This study investigates the early effects of PGF2α signaling on mitochondrial dynamics and mitophagy in bovine corpora lutea. Luteolytic mediator PGF2α, via PKC/ERK and AMPK signaling, activates mitochondrial fission and… Click to show full abstract

This study investigates the early effects of PGF2α signaling on mitochondrial dynamics and mitophagy in bovine corpora lutea. Luteolytic mediator PGF2α, via PKC/ERK and AMPK signaling, activates mitochondrial fission and promotes PINK–Parkin mitophagy, placing mitochondria as novel targets in response to PGF2α.

Keywords: prostaglandin regulates; mitochondrial dynamics; regulates mitochondrial; dynamics mitophagy; bovine corpus; mitophagy bovine

Journal Title: Life Science Alliance
Year Published: 2023

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