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Contextualising evidence based medicine in determining the key root for translational effectiveness for chronic disease self-management and heart failure.

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BACKGROUND Congestive heart failure (CHF) management has proven devastating on morbidity, mortality, quality of life and also costly to health systems. Therapeutics for CHF have advanced and benefited greatly due… Click to show full abstract

BACKGROUND Congestive heart failure (CHF) management has proven devastating on morbidity, mortality, quality of life and also costly to health systems. Therapeutics for CHF have advanced and benefited greatly due to large multicentre randomised controlled trials and the evidence obtained from them. Management for chronic diseases and nonpharmaceutical therapies such as chronic disease self-management has lagged, and for CHF the evidence base has even been questioned. METHODS Perspective and non systematic mini review. CONCLUSIONS Advancing translational research standards is important to achieve optimal cost effectiveness. Importantly is understanding evidence generation in medicine, identifying the primary roots for management and its translation.

Keywords: disease self; heart failure; chronic disease; management; evidence; medicine

Journal Title: Reviews in cardiovascular medicine
Year Published: 2022

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