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We examined the effect of 1α-hydroxyvitamin D3 [1α(OH)D3] on mice in the forced swimming test. Intragastric administration of 1.0 μg/kg of 1α(OH)D3 reduced immobility time in the forced swimming test.… Click to show full abstract
We examined the effect of 1α-hydroxyvitamin D3 [1α(OH)D3] on mice in the forced swimming test. Intragastric administration of 1.0 μg/kg of 1α(OH)D3 reduced immobility time in the forced swimming test. At all concentrations tested (0.5, 1.0, 2.0 μg/kg), 1α(OH)D3 had no effect on locomotor activity, compared with controls. These results suggest that 1α(OH)D3 may have antidepressant-like activity.
Keywords:
effect hydroxyvitamin;
forced swimming;
swimming test;
hydroxyvitamin mice
Journal Title: Journal of nutritional science and vitaminology
Year Published: 2017
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Journal Title: Journal of nutritional science and vitaminology
Year Published: 2017
Link to full text (if available)
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recommendations!