LAUSR

SARS-CoV-2 firstly emerged in China and sporadically transmitted worldwide. In March 2020, WHO announced that the infection was a pandemic. The outbreak and rapid transmission of COVID-19 have endangered the global health and the economy. This crisis has called for an extensive scientific mobilization of studies on SARS-CoV-2 concerning its clinical aspects, characteristics, and its mechanism of transmission. Although many scientists have published the treatment options against COVID-19, currently, there is not any approved medications against the virus yet. COVID-19 vaccine development has started in many research centers and pharmaceutical industries following the announcement of the agent and the full genome of SARS-CoV-2 recognized. Recently, the collected data described that COVID-19 vaccine candidates grouped into the following types: protein-based, epitope, inactivated or live-attenuated virus, virus-like particle, nucleic acid-based, and viral vectors. Therefore, the present review gives a sneak peek of recent updates on COVID-19 vaccine construction worldwide and COVID-19 vaccine’s acceptance in Indonesia.