LAUSR

The purpose of the study was to determine the structural dynamics of healing and skin regeneration characteristics after thermal burns in laboratory rodents in an artificial local regeneration environment - the burn surface is protected by the dome of the device filled with regularly replaced sterile isotonic saline solution. The article presents characteristics of the inflammatory response reaction to steam burns and subsequent skin regeneration in the following comparative aspect: during natural healing under the eschar and in case of constant contact of the burn surface with solutions. Scientific novelty consists in the study of changes in the inflammatory and regenerative response depending on the state of state of aggregation of matter interacting with a wound. It was concluded that secondary skin alteration and fibrous changes in water environment are much lower with considerably higher degree of regeneration. These data can serve as the basis for new regenerative technologies in combustiology.