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Exploiting a Step in Diterpenoid Biosynthesis by the Fungus Fusarium Fujikuroi

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The scope of the microbiological transformation of ent-kaurenoid diterpenes by the fungus Fusarium (Gibberella) fujikuroi which utilise the ent-kaurene and ent-kauren-19-oic acid oxidases and the ring contraction of ring B… Click to show full abstract

The scope of the microbiological transformation of ent-kaurenoid diterpenes by the fungus Fusarium (Gibberella) fujikuroi which utilise the ent-kaurene and ent-kauren-19-oic acid oxidases and the ring contraction of ring B to gibberellin is reviewed. Constraints arising from the presence of 3α, 15α and 18-hydroxyl groups are noted. The development of a group of potential plant growth regulators which inhibit the ring contraction step in gibberellin biosynthesis is described.

Keywords: biosynthesis; step diterpenoid; fungus fusarium; exploiting step; fujikuroi

Journal Title: Journal of Chemical Research
Year Published: 2017

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