The regiospecific synthesis of three quercetin O-β-glucosides of N-acetylglucosamine has been achieved in good yield. Selective di-and tri-O-benzylation of quercetin followed by O-glycosylation with 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl chloride under phase-transfer catalysis conditions… Click to show full abstract
The regiospecific synthesis of three quercetin O-β-glucosides of N-acetylglucosamine has been achieved in good yield. Selective di-and tri-O-benzylation of quercetin followed by O-glycosylation with 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl chloride under phase-transfer catalysis conditions yielded, after deacetylation and debenzylation, 3-, 3′- and 4′-glycosylated quercetin.
Keywords:
regiospecific synthesis;
glucosides acetylglucosamine;
three quercetin;
quercetin glucosides;
quercetin;
synthesis three
Journal Title: Journal of Chemical Research
Year Published: 2018
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Journal Title: Journal of Chemical Research
Year Published: 2018
Link to full text (if available)
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