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Detection of Spotted Fever Group Rickettsia DNA by Deep Sequencing

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After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R.… Click to show full abstract

After conventional molecular and serologic testing failed to diagnose the cause of illness, deep sequencing identified spotted fever group Rickettsia DNA in a patient’s blood sample. Sequences belonged to R. honei, the causative agent of Flinders Island spotted fever. Next-generation sequencing is proving to be a useful tool for clinical diagnostics.

Keywords: fever group; rickettsia dna; group rickettsia; spotted fever; deep sequencing

Journal Title: Emerging Infectious Diseases
Year Published: 2017

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