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Use of Favipiravir to Treat Lassa Virus Infection in Macaques

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Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early… Click to show full abstract

Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir in Lassa virus–viremic macaques and found that 300 mg/kg daily for 2 weeks successfully treated infection.

Keywords: infection; lassa; use favipiravir; lassa virus; favipiravir treat

Journal Title: Emerging Infectious Diseases
Year Published: 2018

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