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Combination of Clindamycin and Azithromycin as Alternative Treatment for Toxoplasma gondii Encephalitis

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Current standard therapies for toxoplasmic encephalitis often cause severe adverse events. A 57-year-old HIV-positive man in Japan who had toxoplasmic encephalitis but was intolerant to trimethoprim/sulfamethoxazole, pyrimethamine, sulfadiazine, and atovaquone… Click to show full abstract

Current standard therapies for toxoplasmic encephalitis often cause severe adverse events. A 57-year-old HIV-positive man in Japan who had toxoplasmic encephalitis but was intolerant to trimethoprim/sulfamethoxazole, pyrimethamine, sulfadiazine, and atovaquone was successfully treated with the combination of clindamycin and azithromycin. This drug combination can be an alternative treatment for this condition.

Keywords: combination; clindamycin azithromycin; encephalitis; alternative treatment; combination clindamycin

Journal Title: Emerging Infectious Diseases
Year Published: 2019

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