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Metagenomics of Imported Multidrug-Resistant Mycobacterium leprae, Saudi Arabia, 2017

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Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations… Click to show full abstract

Using shotgun metagenomics, we identified an imported case of multidrug-resistant Mycobacterium leprae in a Filipino resident of Saudi Arabia in 2017. We determined the phylogenomic lineage (3K1) and identified mutations in rpoB and rrs corresponding to the multidrug-resistance phenotype clinically observed. Metagenomics sequencing can be used to identify multidrug-resistant M. leprae.

Keywords: resistant mycobacterium; leprae; arabia 2017; saudi arabia; mycobacterium leprae; multidrug resistant

Journal Title: Emerging Infectious Diseases
Year Published: 2020

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