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Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

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Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in… Click to show full abstract

Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

Keywords: sarbecovirus; characterization bat; phylogenetically related; detection characterization; sarbecovirus phylogenetically

Journal Title: Emerging Infectious Diseases
Year Published: 2020

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