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Relationship of SARS-CoV-2 Antigen and Reverse Transcription PCR Positivity for Viral Cultures

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We assessed the relationship between antigen and reverse transcription PCR (RT-PCR) test positivity and successful virus isolation. We found that antigen test results were more predictive of virus recovery than… Click to show full abstract

We assessed the relationship between antigen and reverse transcription PCR (RT-PCR) test positivity and successful virus isolation. We found that antigen test results were more predictive of virus recovery than RT-PCR results. However, virus was isolated from some antigen-negative and RT-PCR‒positive paired specimens, providing support for the Centers for Disease Control and Prevention antigen testing algorithm.

Keywords: relationship; pcr; antigen; antigen reverse; reverse transcription; transcription pcr

Journal Title: Emerging Infectious Diseases
Year Published: 2022

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