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Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA

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We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome RNA sequencing of measles virus from brain tissue.… Click to show full abstract

We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome RNA sequencing of measles virus from brain tissue. We observed biased matrix-gene hypermutation consistent with persistent measles virus central nervous system infection.

Keywords: child california; immunocompromised child; measles encephalitis; associated measles; encephalitis immunocompromised; vaccine associated

Journal Title: Emerging Infectious Diseases
Year Published: 2022

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