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Possible Mpox Protection from Smallpox Vaccine–Generated Antibodies among Older Adults

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Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among… Click to show full abstract

Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71–80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.

Keywords: mpox; protection; smallpox vaccine; protection smallpox; possible mpox; mpox protection

Journal Title: Emerging Infectious Diseases
Year Published: 2023

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