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Detection of Severe Murine Typhus by Nanopore Targeted Sequencing, China

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We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore… Click to show full abstract

We report a case of murine typhus in China caused by Rickettsia typhi and diagnosed by nanopore targeted sequencing of a bronchoalveolar lavage fluid sample. This case highlights that nanopore targeted sequencing can effectively detect clinically unexplained infections and be especially useful for detecting infections in patients without typical signs and symptoms.

Keywords: nanopore targeted; targeted sequencing; murine typhus; detection severe; severe murine

Journal Title: Emerging Infectious Diseases
Year Published: 2023

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