LAUSR

BACKGROUND Currently, quadrilateral anterior cervical plate (QACP) is a highly prevalent ACP. OBJECTIVE This study aims to design a novel ACP using topology optimization (TOACP). METHODS A completed model for C1-C7 cervical segments was established and validated. QACP and TOACP cage systems were implanted within two cervical vertebrae models, respectively, and peak stresses and stress distributions for screw, plate, endplate and cage displacement were investigated under differing exercise modes. RESULTS Stress levels upon QACP screw were maximized for over-extension exercise (243.3 MPa, 3.35% > TOACP screw). Stress level upon TOACP plate was maximized for over-extension exercise (118.2 MPa, 7.26% > QACP screw). Following QACP cage system implantation, stress on endplate and cage displacement were maximized for extension exercise, which were 27.1%, and 6.3% > TOACP cage system, respectively. Finite element analysis results revealed that topological optimization of the plate can effectively reduce screw stress, thereby enhancing cervical segments' stability during surgery. Furthermore, stress on endplate and cage displacement decreased, indicating great potential in cage sinking and fusion enhancement. CONCLUSIONS Topological optimization of the plate equips the cage system with advantages in clinical applications and biomechanical performance, providing alternative solutions and a theoretical basis for ACP design.