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A bedside ultrasound protocol to the measurement of the systemic vascular resistances: Preliminary results in the patients with sepsis.

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BACKGROUND The use of the ultrasound (US) bedside examination is increasing for the detailed evaluation of the hemodynamic parameters, allowing the physicians to set the appropriate therapeutic strategies with greater… Click to show full abstract

BACKGROUND The use of the ultrasound (US) bedside examination is increasing for the detailed evaluation of the hemodynamic parameters, allowing the physicians to set the appropriate therapeutic strategies with greater precision. OBJECTIVE The aim of this study is to evaluate the hemodynamic parameters (the cardiac output or CO, the central venous pressure or CVP and the systemic vascular resistance or SVR) in the patients with sepsis, by using a bedside US approach. METHODS We consecutively enrolled n.82 patients of S.Andrea Hospital (n.47 with sepsis and n.35 without sepsis), examining the hemodynamic parameters by a bedside US evaluation. RESULTS The incidence of sepsis was more than 50% of cases. The patients with sepsis presented higher comorbidity and polypharmacy (p <  0.01, p <  0.001), with increased creatinine (p <  0.001) and esteemed glomerular filtration rate (p <  0.01), C-reactive protein (p <  0.01), SOFA (Sepsis-related Organ Failure Assessment) score (p <  1.58×10-7) and reduced SVR (p <  0.05).The SOFA score was inversely related to the SVR (p <  0.05). CONCLUSIONS To our best knowledge, this is the first study with a bedside US protocol to measure SVR, beyond the abdominal and cardiac qualitative evaluation.

Keywords: sepsis; ultrasound protocol; hemodynamic parameters; patients sepsis; bedside ultrasound; systemic vascular

Journal Title: Clinical hemorheology and microcirculation
Year Published: 2022

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