LAUSR

BACKGROUND: Knowledge regarding the hypothalamic nuclei is essential for understanding neuroanatomy and has substantial clinical relevance. OBJECTIVE: The aim was to contribute to elucidate the complex hypothalamic architecture for research and provide an anatomical basis for clinical brain operation. METHODS: In this research, high-resolution and true-color sectioned images from Visible Korean were employed for hypothalamic nuclei and neighboring structures surface modeling, and a high-resolution three-dimensional atlas of the hypothalamus was created. RESULTS: Surface models of 26 structures including the hypothalamic nuclei and its neighboring structures were produced, which contained 5 anterior hypothalamic areas’ nuclei, 4 intermediate hypothalamic areas’ nuclei, 3 lateral hypothalamic areas’ nuclei, and 2 posterior hypothalamic areas’ nuclei, as well as 12 hypothalamic neighboring structures. CONCLUSIONS: The study evaluated the topographical anatomy of the hypothalamic nuclei and its neighboring structures based on true-color and highresolution sectioned images of Visible Korean.