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Pyruvate kinase deficiency (PKD) is the most frequent glycolytic enzyme defect causing hereditary non-spherocytic hemolytic anemia.[1][1] PKD leads to energy deprivation of the red cell, ultimately resulting in premature red… Click to show full abstract
Pyruvate kinase deficiency (PKD) is the most frequent glycolytic enzyme defect causing hereditary non-spherocytic hemolytic anemia.[1][1] PKD leads to energy deprivation of the red cell, ultimately resulting in premature red cell death. Premature red cell death causes clinical symptoms of hemolytic
Keywords:
pyruvate kinase;
kinase deficiency;
cell
Journal Title: Haematologica
Year Published: 2018
Link to full text (if available)
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Journal Title: Haematologica
Year Published: 2018
Link to full text (if available)
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recommendations!