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Lenalidomide plus bendamustine-rituximab does not overcome the adverse impact of TP53 mutations in mantle cell lymphoma

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TP53 mutations are associated with significant poorer outcomes in mantle cell lymphoma (MCL), and new treatment strategies are highly warranted. Lenalidomide has shown high efficacy in MCL; however, there is… Click to show full abstract

TP53 mutations are associated with significant poorer outcomes in mantle cell lymphoma (MCL), and new treatment strategies are highly warranted. Lenalidomide has shown high efficacy in MCL; however, there is no knowledge of its effect on TP53 mutated cases. In this study, we show that the addition

Keywords: plus bendamustine; lenalidomide plus; mantle cell; tp53; tp53 mutations; cell lymphoma

Journal Title: Haematologica
Year Published: 2018

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