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TP53, ETV6 and RUNX1 germline variants in a case series of patients developing secondary neoplasms after treatment for childhood acute lymphoblastic leukemia

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Today, most children with acute lymphoblastic leukemia (ALL) can be cured by treatment regimens consisting of combination chemotherapy supplemented in certain patient populations with preventive or therapeutic cranial irradiation (CI)… Click to show full abstract

Today, most children with acute lymphoblastic leukemia (ALL) can be cured by treatment regimens consisting of combination chemotherapy supplemented in certain patient populations with preventive or therapeutic cranial irradiation (CI) and/or an allogeneic hematopoietic stem cell transplantation (

Keywords: etv6 runx1; treatment; lymphoblastic leukemia; tp53 etv6; acute lymphoblastic

Journal Title: Haematologica
Year Published: 2019

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