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CHARACTRISTICS OF PHOSPHORIC­CALCIUM METABOLISM AT VARIOUS LEVELS OF 25(OH)D IN CHILDREN AND ADOLESCENTS RESIDENTS OF THE ARCTIC ZONE OF THE RUSSIAN FEDERATION

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The aim: to reveal dependence of phosphoric-calcium metabolism рarameters from 25(OH)D level in children and adolescents living in the conditions of Arctic Zone of Russia. Methods: Sampling included 430 children… Click to show full abstract

The aim: to reveal dependence of phosphoric-calcium metabolism рarameters from 25(OH)D level in children and adolescents living in the conditions of Arctic Zone of Russia. Methods: Sampling included 430 children and adolescents (age from 7 to 16 years), 192 (45 %) boys, 238 (55 %) girls. 25-OH vitamin D, parathyroid hormone, total calcium, phosphorus, alkaline phosphatase in blood serum concentration was estimated. Results: Normal findings of D vitamin were found in 95 (22 %) surveyed, 25(OH)D deficiency in the blood plasma = 20-30 ng / ml was found in 61 (14 %) surveyed, 25(OH)D deficit = 10-19 ng / ml was detected in 205 (48 %) and 25(OH)D strong deficit < 10 ng / ml - in 68 (16 %) of the examined patients. The absence of parathyroid hormone increase in case of D vitamin deficit was revealed in 96,1 % of surveyed. Conclusion: Low levels of vitamin D were found in children and adolescents in the region, whereas no increase in the level of parathyroid hormone typical for rickets was found.

Keywords: phosphoric calcium; arctic zone; children adolescents; calcium; calcium metabolism

Journal Title: Human Ecology
Year Published: 2018

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