Platelet satellitism (PS) is a rare cause of pseudothrombocytopenia due to the adhesion of platelets to the surfaces of circulating leukocytes. PS occurs when circulating auto-antibodies bind to cryptic antigens… Click to show full abstract
Platelet satellitism (PS) is a rare cause of pseudothrombocytopenia due to the adhesion of platelets to the surfaces of circulating leukocytes. PS occurs when circulating auto-antibodies bind to cryptic antigens exposed because of the calcium-chelating activity of EDTA [1]. The antibody–platelet antigen (antiglycopro-tein IIb/IIIa) binds to the Fc γ receptor (CD16) on the cell surface, resulting in the typical PS results in blood smear images [2]. PS can be associated with platelet phagocytosis by neutrophils or, less frequently, monocytes [3]. PS accounts for less than 1% of total pseudothrombocytopenia cases. The reported yearly incidence of 1:12,000 may be underestimated as PS does not cause remarkable scattergram abnormalities in most cases and is usually detected using light microscopy [2]. We report a case of PS around neutrophils, monocytes, and lymphocytes, associated with platelet phagocytosis. The requirement for informed consent was waived by the Institutional Ethics Com-mittees because of the retrospective nature of this study based on a case that occurred in 2017. A
               
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