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Exploring the mythical abscopal effect: Radiation and programmed cell death protein 1 (PD-1) blockade for hepatocellular carcinoma

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Corresponding author : Ik Jae Lee Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea Tel: +82-2-2019-3152, Fax: +82-2-2019-4855 E-mail: [email protected]Click to show full abstract

Corresponding author : Ik Jae Lee Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea Tel: +82-2-2019-3152, Fax: +82-2-2019-4855 E-mail: [email protected] https://orcid.org/0000-0001-7165-3373 Abbreviations: cGAS, cyclic GMP-AMP synthase; CTLA-4, cytotoxic T-lymphocyte-associated protein 4; DCs, dendritic cells; HCC, hepatocellular carcinoma; ICIs, immune checkpoint inhibitors; ICV, inferior vena cava; PD-1, programmed cell death protein 1; SBRT, stereotactic body radiotherapy; STING, stimulator of interferon genes; TDLNs, tumor-draining lymph nodes

Keywords: protein; hepatocellular carcinoma; death protein; programmed cell; cell death; radiation

Journal Title: Clinical and Molecular Hepatology
Year Published: 2020

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