LAUSR

We would like to share ideas on “COVID-19 vaccine immunogenicity among chronic liver disease patients and liver transplant recipients: A meta-analysis [1].” In contrast to LT recipients, CLD patients exhibited a good humoral response to the COVID-19 vaccination, according to Cheung et al. [1]. We both agree that COVID-19 is helpful in immunogenicity. The immunological response of a vaccine recipient with an underlying medical condition may be different from that of a healthy individual. The potential confounding factors must be taken into consideration while interpreting the current report. Prior asymptomatic COVID-19 infection is a possibility and is not unusual [2]. If there is no method to rule out prior asymptomatic COVID-19, it is challenging to evaluate the vaccine's effectiveness.