LAUSR

Chronic hepatitis B virus (HBV) infections, leading to approximately 650,000 fatalities annually, is a major global health burden. Understanding the interaction between HBV and host liver cells will contribute to develop diagnosis and treatment of liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Mitochondrial dysfunction is a common feature that results from viral infection, causing the accumulation of reactive oxygen species and the activation of cell senescence. In this Research Topic, innovative approaches are applied to explore the function of mitochondria and cell senescence in liver disease progression, and to monitor the effectiveness in antiviral treatment. Finally, five interesting original research articles are accepted in this Research Topic.