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Two supramolecular nanomedicines (CB[7]⊃DOX and CB[7]⊃CPT) based on the host–guest recognition between CB[7] and anticancer drugs were constructed. After supramolecular modification, the stability and water solubility of DOX and CPT… Click to show full abstract
Two supramolecular nanomedicines (CB[7]⊃DOX and CB[7]⊃CPT) based on the host–guest recognition between CB[7] and anticancer drugs were constructed. After supramolecular modification, the stability and water solubility of DOX and CPT were greatly improved, and the anticancer activities of chemotherapeutic drugs were effectively maintained. This work provided a simple but efficient method to enrich supramolecular nanomedicines for cancer therapy.
Keywords:
cucurbit uril;
supramolecular nanomedicine;
construction cucurbit;
uril based;
therapy;
based supramolecular
Journal Title: Frontiers in Chemistry
Year Published: 2022
Link to full text (if available)
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Journal Title: Frontiers in Chemistry
Year Published: 2022
Link to full text (if available)
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recommendations!